Lipi Thukral, IGIB, Delhi
1. Jatana N, Ascher BD, Pires EVD, Gokhale RS, Thukral L. Human LC3 and GABARAP subfamily members achieve functional specificity via specific structural modulations. Autophagy. 2019. Accepted.
2. Ray A, Ghosh A, Chakraborty R, Upadhyay SK, Maiti S, Sengupta S, Thukral L. Specific Cholesterol Binding Drives Drastic Structural Alterations in Apolipoprotein A1. J Phys Chem Lett. 2018 18;9(20):6060-6065.
3. Ramkumar A, Murthy D, Raja DA, Singh A, Krishnan A, Khanna S, Vats A, Thukral L, Sharma P, Sivasubbu S, Rani R, Natarajan VT, Gokhale RS. Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks. Autophagy.2017;13(8):1331-1347.
4. Nagpal S, Tiwari S, Mapa K, Thukral L. Decoding structural properties of a partially unfolded protein substrate: en route to chaperone binding. PLoS Comput. Biol. 2015; 11(9):e1004496.
Ravi Manjithaya, JNCASR, Bangalore
1. Barve, G., Sridhar, S., Aher, A., Sahani, M.H., Chinchwadkar, S., Singh, S., Lakshmeesha, K.N., McMurray, M.A., and Manjithaya, R. (2018). Septins are involved at the early stages of macroautophagy in S. cerevisiae. J Cell Sci 131.
2. Mishra, P., Dauphinee, A.N., Ward, C., Sarkar, S., Gunawardena, A., and Manjithaya, R. (2017). Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms. Autophagy 13, 1556-1572.
3. Suresh, S.N., Chavalmane, A.K., Dj, V., Yarreiphang, H., Rai, S., Paul, A., Clement, J.P., Alladi, P.A., and Manjithaya, R. (2017). A novel autophagy modulator 6-Bio ameliorates SNCA/alpha-synuclein toxicity. Autophagy 13, 1221-1234.
Santosh Chauhan, ILS, Bhubaneswar
1. Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S. The Crohn's disease risk factor IRGM limits NLRP3 inflammasome activation by impeding its assembly and by mediating its selective autophagy. Molecular Cell. 2019 Feb 7;73(3):429-445.e7.
(Preview: Nabar NR, Kehrl JH. Inflammasome Inhibition Links IRGM to Innate Immunity. Molecular Cell. 2019 Feb 7;73(3):391-392)
2. Jena KK, Kolapalli SP, Mehto S, Nath P, Das B, Sahoo PK, Ahad A, Syed GH, Raghav SK, Senapati S, Chauhan S, Chauhan S. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018 Sep 14;37(18).
3. Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd MH, Kimura T, Choi SW, Peters R, Mandell M, Bruun JA, Johansen T, Deretic V. TRIMs and Galectins globally cooperate and TRIM16 and Galectin-3 codirect autophagy in endomembrane damage homeostasis. Developmental Cell. 2016 Oct 10;39(1):13-27.
Rajdeep Chowdhary, BITS, Pillani
1. Autophagy regulated by gain of function mutant p53 enhances proteasomal inhibitor-mediated cell death through induction of ROS and ERK in lung cancer cells. Saini H, Hakeem I, Mukherjee S, Chowdhury S, and Chowdhury R*. Journal of Oncology; 6164807; 2019.
2. TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment. Dash S, Prasad M.S., Balaji R, Chowdhury R* and Mukherjee S* (*corresponding authors). Oncotarget; 2018; 9:6433-6449.
3. The dynamic role of autophagy and MAPK signaling in determining cell fate under cisplatin stress. Mukherjee S, Dash S, Lohitesh K and Chowdhury R*. PloS One..2017, 12(6): e0179203.
Manjula Kalia, RCB, Faridabad
1. Khasa, R., Vaidya, A., Vrati, S., and Kalia, M. (2019). Membrane trafficking RNA interference screen identifies a crucial role of the clathrin endocytic pathway and ARP2/3 complex for Japanese encephalitis virus infection in HeLa cells. J Gen Virol 100, 176-186.
2. Nain, M., Mukherjee, S., Karmakar, S.P., Paton, A.W., Paton, J.C., Abdin, M.Z., Basu, A., Kalia, M., and Vrati, S. (2017). GRP78 Is an Important Host Factor for Japanese Encephalitis Virus Entry and Replication in Mammalian Cells. J Virol 91.
3. Sharma, M., Bhattacharyya, S., Sharma, K.B., Chauhan, S., Asthana, S., Abdin, M.Z., Vrati, S., and Kalia, M. (2017). Japanese encephalitis virus activates autophagy through XBP1 and ATF6 ER stress sensors in neuronal cells. J Gen Virol 98, 1027-1039.
4. Sharma, M., Sharma, K.B., Chauhan, S., Bhattacharyya, S., Vrati, S., and Kalia, M. (2018). Diphenyleneiodonium enhances oxidative stress and inhibits Japanese encephalitis virus induced autophagy and ER stress pathways. Biochem Biophys Res Commun 502, 232-237. 1)
Ashwani Kumar, IMTECH, Chandigarh
1. Nisha Singh, Pallavi Kansal, Zeeshan Ahmad, Navin Baid, Hariom Kushwaha, Neeraj Khatri, Ashwani Kumar. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis. Autophagy. 2018. DOI: 10.1080/15548627.2018.1436936.
2. Nisha Singh, Asheema Vats, Aditi Sharma, Amit Arora, Ashwani Kumar. The development of lower respiratory tract microbiome in mice. Microbiome. 2017, 5:61 https://doi.org/10.1186/s40168-017-0277-3
3. Abhishek Trivedi, Parminder Singh Mavi, Deepak Bhatt & Ashwani Kumar. Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis. Nature communications 2016 Apr 25;7:11392. doi: 10.1038/ncomms11392.
4. Shabir Ahmad Bhat, Iram Khan Iqbal and Ashwani Kumar. Imaging the NADH:NAD+ homeostasis for understanding the metabolic response of Mycobacterium to physiologically relevant stresses. Frontiers in Cellular and Infection Microbiology. 6:145 doi: 10.3389/fcimb.2016.00145.
Anirban Banerjee, IIT, Mumbai
1. Surve MV, Bhutda S, Datey A, Anil A, Rawat S, Pushpakaran A, Singh D, Kim KS, Charavotty D, Banerjee A. Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking. PLoS Pathogens. 2018, 14(7): e1007168.
2. Surve MV, Anil A, Kamath KG, Bhutda S, Sthanam KL, Pradhan A, Srivastava R, Basu B, Dutta S, Sen S, Modi D, Banerjee A. Membrane vesicles of Group B Streptococcus disrupt feto-maternal barrier leading to preterm birth. PLoS Pathogens. 2016, 12: e1005816.
3. Sangabathuni S, Vasudeva MR, Chaudhary PM, Surve M, Banerjee A, Kikkeri R. Glyco-gold nanoparticle shapes enhance carbohydrate-protein interactions in mammalian cells. Nanoscale. 2016, 8:12729-12735.
Sarika Gupta, NII, Delhi
1. Manglani K, Vijayan V, Pathak C, Khandelwal M, Singh P, Chellappa S, Yadav VK, Surolia A, Gupta S*. .Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process. Bone. 2019 Feb 21;122:123-135. doi: 10.1016/j.bone.2019.02.019. [Epub ahead of print]
2. Khan J, Salhotra S, Ahmad S, Sharma S, Abdi SAH, Banerjee BD, Parvez S, Gupta S*, Raisuddin S*. The protective effect of α-lipoic acid against bisphenol A-induced neurobehavioral toxicity.Neurochem Int. 2018 Sep;118:166-175. doi: 10.1016/j.neuint.2018.06.005. Epub 2018 Jun 13.
3. Benzothiophenes as Potent Analgesics Against Neuropathic Pain. Yadav S, Dwivedi VK, Gupta S, Surolia A. Adv Exp Med Biol. 2018;1112:245-254. doi: 10.1007/978-981-13-3065-0_17.
4. Ahsan N, Siddique IA, Gupta S*, Surolia A*. A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity. Eur J Med Chem. 2018 Jan 1;143:1174-1184.
5. Bipin Kumar Gupta*, Pawan Kumar,Garima Kedawat,Kanika, Sajna Antony Vithayathil,Amit Kumar Gangwar,Satbir Singh, Pradeep Kumar Kashyap,Rimli Lahon,V. N. Singh,Abhay D. Deshmukh, Tharangattu N. Narayanan,Nidhi Singh,Sarika Guptaand Benny Abraham Kaipparettu*. Tunable luminescence from two dimensional BCNO nanophosphor for high-contrast cellular imaging. RSC Adv., 2017, 7, 41486
6. Viji Vijayan*, Sakshi Gupta Sarika Gupta* (2017). Bone morphogenetic protein-5, a key molecule that mediates differentiation in MC3T3E1 osteoblast cell line. Biofactors, May 12. doi: 10.1002/biof.1360.
Dhiraj Kumar, ICGEB, Delhi
1. Chandra, P., and Kumar, D. (2016). Selective autophagy gets more selective: Uncoupling of autophagy flux and xenophagy flux in Mycobacterium tuberculosis-infected macrophages. Autophagy 12, 608-609.
2. Kalam, H., Fontana, M.F., and Kumar, D. (2017). Alternate splicing of transcripts shape macrophage response to Mycobacterium tuberculosis infection. PLoS pathogens 13, e1006236.
3. Vashi, N., Andrabi, S.B., Ghanwat, S., Suar, M., and Kumar, D. (2017). Ca2+-dependent Focal Exocytosis of Golgi-derived Vesicles Helps Phagocytic Uptake in Macrophages. The Journal of biological chemistry 292, 5144-5165.